Barua Lab

The Barua lab has garnered international profile on the basis of their unique genetic observations and ongoing efforts to establish biologic mechanism linking gene mutations to chronic kidney disease. The Barua lab’s goal is to improve diagnosis and by defining the genetic basis of clinical syndromes previously labelled as idiopathic, to have important impact on therapeutic development.

About Us

Dr. Moumita Barua is a Senior Scientist at the Toronto General Hospital Research Institute. She is Associate Director of the Hereditary Kidney Disease Clinic, where individuals with genetic conditions affecting the kidney are seen.

A major contribution of the Barua Lab has been the identification of variants in the α3, α4 and α5 chains of type IV collagen in hematuria, albuminuria and a pathologic lesion known as focal and segmental glomerulosclerosis (FSGS). The Barua lab has also identified PAX2 mutations in FSGS. These findings form the basis of mechanistic work that the group is now pursuing alongside their human genetic studies.

Leadership

  • Dr. Moumita Barua
    Associate Director - Hereditary Kidney Disease Clinic
    Senior Scientist - Division of Nephrology, UHN

Awards

  • 2021-24

    Clinician Scientist Merit Award

    Awarded by the Department of Medicine, University of Toronto.

  • 2021

    Mimi and Charles Hollenberg Research Award

    This award is named after Dr. Charles Hollenberg, whose legacy in academic medical research still impacts lives today.

  • 2018-19

    Mimi and Charles Hollenberg Research Award, Category 2 (Clinical Epidemiology), Second Place: Khalil Udwan - Under Supervision of Dr. Barua

    This award is named after Dr. Charles Hollenberg, whose legacy in academic medical research still impacts lives today.

  • 2016-19

    KRESCENT Award

    Awarded by the Canadian Institutes of Health Research and Kidney Foundation of Canada.

  • 2016

    1st Place - Great Cases in Medicine Competition

    Awarded by University Health Network and Mount Sinai Hospital.

  • 2009

    Mimi and Charles Hollenberg Research Award, Category 2 (Clinical Epidemiology)

    Award named after Dr. Charles Hollenberg, whose legacy in academic medical research still impacts lives today.

Publications